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Dr. Mario
马里奥：Dr.
Dr. Mario is a puzzle game released by Nintendo in 1990 for the NES. Players control Dr. Mario and drop colored capsules (red, yellow, blue) down a vertical playfield to eliminate viruses of matching colors. The objective is to clear all viruses by forming chains of four or more identical colors horizontally, vertically, or diagonally. The game features increasing difficulty across multiple levels, with faster falling speeds and more complex virus arrangements. Controls are straightforward: left and right arrows move the capsule, up rotates it. Two-player mode offers competitive gameplay where players face off in separate playfields. The puzzle mechanics require planning and quick reflexes as capsules fall steadily. Progress through stages presents escalating challenges, making it both accessible to newcomers and engaging for experienced players.
- Developer
- Nintendo
- Released
- 1990
- Platform
- NES
- Genre
- Puzzle
- Players
- 2P
- Rating
- 4.5 / 5 (1.8K)
- Last updated
Dr. Mario Controls — NES Keyboard Keys
Default keyboard bindings for Dr. Mario on our in-browser NES emulator. Plug in a USB or Bluetooth gamepad to auto-detect mappings, or rebind any key from the emulator settings menu.
| Keyboard | Console button | Typical use |
|---|---|---|
| ↑ | D-Pad Up | Move up |
| ↓ | D-Pad Down | Move down |
| ← | D-Pad Left | Move left |
| → | D-Pad Right | Move right |
| X | A | Primary action (jump / confirm) |
| Z | B | Secondary action (attack / cancel) |
| Enter | Start | Start / Pause |
| Shift | Select | Select / Mode |
Rebind any key from the EmulatorJS in-game settings menu (gear icon → Controls). A connected gamepad auto-maps to the same buttons.
Dr. Mario Longplay & Gameplay Videos
Watch a full playthrough of Dr. Mario on NES before you dive in — recommended for getting a feel for the game's pacing, story beats, and difficulty curve.
Watch longplay on YouTube
"Dr. Mario" NES longplay 1990
Dr. Mario Cheat Codes
30 community-curated cheats for Dr. Mario. Tick any to activate them automatically when you click "Play with cheats" — or copy a code into your own emulator.
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Can Select Up To Level 24
APEONLGOAONPSZGO -
Vitamin capsules don't fall
GZNEVIVT -
5 in a row needed to complete a vertical (upright) line instead of 4
GEXPYGLA -
6 in a row needed to complete a vertical line instead of 4
IEXPYGLA -
7 in a row needed to complete a vertical line instead of 4
TEXPYGLA -
5 in a row needed to complete a horizontal (flat) line instead of 4
GAKPPZLA -
6 in a row needed to complete a horizontal line instead of 4
IAKPPZLA -
7 in a row needed to complete a horizontal line instead of 4
TAKPPZLA -
More pieces sent across to other player
AUVONUAO -
No pieces sent across to other player
GXXOZGVT+GZKPGZVT -
Virus Level Modifier (0-14)
0316:00 -
Virus Remaining Modifier (Ignore HUD)
0324:00
Show 18 more cheats Show fewer
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Score Modifier P1
0728:00+0729:00+072A:00+072B:00+072C:00+072D:00 -
Pill Modifier
031A:00+031B:00 -
Congratulations 1
PESPKPYA -
Chill
ZESPKPYA -
Fever
GESPKPYA -
Game Over
IESPKPYA -
Title Screen
TESPKPYA -
Congratulations 2
AESPKPYE -
Chill Win
PESPKPYE -
Fever Win
ZESPKPYE -
2 Player Win
LESPKPYE -
Congratulations 3
GESPKPYE -
Congratulations 4
IESPKPYE -
DPCM Triangle Volume Controller
TESPKPYE -
Place Pill To Instantly Win Round
GVUPAAAA -
Dusk Mode
ANOLZVTO -
Night Mode
ENOLZVTO -
Sepia Mode
LNOLZVTO
External references
Frequently Asked Questions
When was Dr. Mario released?
Dr. Mario was released in 1990 for the NES.
Who developed Dr. Mario?
Dr. Mario was developed by Nintendo, available to play in your browser on RetroGameSpace.
How many players does Dr. Mario support?
Dr. Mario supports up to 2 players, ideal for couch co-op or competitive sessions on the NES.
What type of game is Dr. Mario?
Dr. Mario is a Puzzle game for the NES, playable instantly in your browser — no downloads, no installs.
How can I play Dr. Mario for free?
Open this page and click "Play Now" — Dr. Mario runs free in your browser via WebAssembly emulation. No account, no payment, no installer.
Do I need to download anything to play Dr. Mario in the browser?
No. Dr. Mario streams from a public archive into a browser-side NES emulator. Nothing is installed on your computer.
Can I save my progress in Dr. Mario?
Yes. Save states are stored in your browser (IndexedDB) per game, and you can also use any in-game save the original NES cartridge supported.
Does Dr. Mario work on mobile devices?
Yes — the NES emulator runs on iOS Safari and Android Chrome. Touch controls overlay the game; landscape mode is recommended.
Is it legal to play Dr. Mario this way?
RetroGameSpace is a transient caching reverse-proxy and does not host first-party copies of Dr. Mario. Game files are fetched on demand from publicly-accessible archives. You are responsible for compliance with your local laws and the bring-your-own-ROM principle.
